They were once labelled “the new heroin” of Tayside and implicated in the deaths of hundreds of people around the country.
But after years of campaigning by activists, new psychoactive substances (NPS) or so-called legal highs will finally become illegal this week.
Local campaigners have declared this a massive step forward in the fight against the dangerous substances.
At one time, even children could buy £10 packets of the substances, which came in colourful and attractive packaging.
It was claimed that youngsters as young as 15 had collapsed at school after experimenting with them in Dundee.
Over the past couple of years it’s become a massive issue in Tayside — with folk telling the Tele how they almost died after taking NPS and battles to stop retailers selling them.
But as of Thursday, it will become a criminal offence to produce, supply, offer to supply, possess with intent to supply, possess on custodial premises and to import or export psychoactive substances that are intended for human consumption.
People caught committing these crimes could face up to seven years in jail.
The authorities will have powers to stop and search people, vehicles and vessels and enter and search premises in accordance with a warrant to seize and destroy the substances.
Jo Roden, 56, of Dryburgh lost two of her sons to drugs, one of whom started on legal highs.
She said: “My initial reaction is one of ‘thank God – it’s about time’.
“I didn’t actually know about it till now but I think this legislation is a great thing.
“I think this will maybe save a generation. I’ve already lost two sons and I don’t want this to happen to anyone else.”
Councillor Georgia Cruickshank, who has helped lead the Dundee Against Legal Highs group, said there was still one shop in the city suspected of selling legal highs, but now she hopes the police will be able to take action in the future.
She said: “I’m absolutely delighted the law is coming in. We have fought long and hard to get the shops selling them closed down and hopefully this will be the end. I’m aware of one shop which is still selling them according to a number of people.
“Our task was to get the shops shut down so that there was less chance of young people and the vulnerable being tempted by them, and by and large we did that.
“I honestly think legal highs will die a death now. I would hope that anyone who continues to sell them will now face swift and prompt police action.
“And certainly, if any information comes my way I will pass it onto the police and trading standards straight away.”
When the Tele visited the shop mentioned by Ms Cruickshank, staff denied they were selling the substances.
Rev Martin Fair, who has fought the sale of legal highs in Arbroath, added: “I don’t think one piece of legislation will solve an issue but it will become part of the armoury in tackling legal highs.”
Deputy Chief Constable Ruaraidh Nicolson said: “Police Scotland will take appropriate and proportionate action to deal with NPS and the impact they have on our communities.
“We have engaged with known sellers of NPS to make them aware of the introduction of the Psychoactive Substances Act 2016. We are working with Trading Standards Scotland and local authority departments in taking action against those who supply NPS.
“There’s no safe way to take NPS. The only way of staying safe is to avoid NPS altogether.”